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This extremely potent synthetic opioid is strictly for in vitro, in vivo animal models, and analytical investigations—not for human or veterinary clinical application.

Carfentanil Powder, chemically identified as methyl 1-(2-phenylethyl)-4-[phenyl(propanoyl)amino] piperidine-4-carboxylate, is a synthetic analogue of fentanyl within the 4-anilidopiperidine class. First developed in 1974 by Janssen Pharmaceutica, it bears the molecular formula C24H30N2O3 and a molar mass of approximately 394.51 g/mol (CAS 59708-52-0).

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As a white crystalline or granular powder in its pure form, Carfentanil is renowned in scientific contexts for its extraordinary potency—approximately 10,000 times that of morphine and 100 times that of fentanyl—making it one of the most powerful mu-opioid receptor agonists available for research.

It is marketed under names like Wildnil for large-animal tranquilization, but in research settings, the powder form enables precise handling in controlled studies of opioid pharmacology.

The mechanism of action for Carfentanil Powder centers on its role as a highly selective and ultrapotent agonist at mu-opioid receptors, with additional affinity for kappa and delta receptors. It binds with subnanomolar affinity (Ki around 0.024–0.051 nM at mu receptors), triggering profound analgesia, sedation, and respiratory effects in experimental models.

Its lipophilic nature allows rapid blood-brain barrier penetration, resulting in quick onset and prolonged duration compared to less potent analogues. In neuropharmacological research, Carfentanil facilitates detailed examination of opioid receptor signaling, receptor occupancy via PET imaging (using radiolabeled forms like [11C]-carfentanil), and structure-activity relationships among fentanyl derivatives.

Researchers use it to model extreme opioid responses, metabolic pathways, and potential countermeasures against ultra-potent synthetic opioids.

Key benefits and advantages of Carfentanil Powder in research include its unmatched potency, which allows microgram-level dosing for sensitive assays and reduces required quantities in experiments. This efficiency supports cost-effective, high-precision studies on mu-opioid receptor dynamics, addiction mechanisms, overdose pathophysiology, and novel antagonist development.

Its selectivity and binding characteristics make it ideal for comparative analyses with fentanyl, sufentanil, and emerging analogues, advancing understanding of opioid tolerance, dependence, and therapeutic interventions.

Many research institutions value its consistency for reproducible data in toxicology, forensic chemistry, and neurobiology projects. Customers consistently express high satisfaction with our product’s quality, noting reliable results that contribute to peer-reviewed publications and grant-funded work.

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Safety and responsible usage considerations are critical due to Carfentanil’s extreme potency. This substance is designated exclusively for laboratory research and is not approved for human use—accidental exposure, even in trace amounts, poses severe risks including rapid respiratory depression.

Researchers must employ stringent protocols: full PPE (nitrile gloves, respirators, eye protection), work in fume hoods or glove boxes, use precise microbalances, and have naloxone or naltrexone reversal agents immediately available (higher doses may be required).

Institutional biosafety and ethics approvals are essential. Side effects in animal models include profound sedation, bradycardia, and apnea; human exposure risks are life-threatening. Our documentation includes detailed safety data sheets to support responsible handling and build confidence in safe practices.

Longevity and storage life for Carfentanil Powder are favorable under proper conditions. With appropriate storage, it maintains stability for 24–36 months or longer. Keep in airtight, light-resistant containers at temperatures below 25°C, in a cool, dry, secure environment away from moisture and oxidizers. Refrigeration (2–8°C) can further extend viability for sensitive applications. This robustness allows bulk purchases for extended research programs without quality loss.

The composition of Carfentanil Powder is 99%+ pure methyl 1-(2-phenylethyl)-4-[phenyl(propanoyl)amino] piperidine-4-carboxylate (free base or salt form), verified via HPLC, NMR, and mass spectrometry with no additives or contaminants. This high purity minimizes experimental variability and ensures accurate dosing in quantitative studies.

Usage areas for research purposes encompass advanced opioid pharmacology, including mu-receptor binding kinetics, PET imaging of opioid systems in brain tissue, toxicology profiling of synthetic opioids, forensic method development for detection in biological matrices, and investigation of overdose reversal strategies.

It supports studies on fentanyl-class compounds’ contributions to public health challenges, metabolic biotransformation, and potential therapeutic analogues. Academic, pharmaceutical, and government labs frequently utilize it for cutting-edge neurochemical and analgesic research.

We prioritize trust through transparency, third-party analytical certificates, and consistent customer feedback highlighting dependable purity and service. Researchers worldwide rely on our Carfentanil Powder for groundbreaking work. Explore our complete range at our homepage: https://purehighz.com/.

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Product Details Table

Attribute Details
Brand PureHighz
Composition / Ingredients Methyl 1-(2-phenylethyl)-4-[phenyl(propanoyl)amino] piperidine-4-carboxylate (C24H30N2O3)
Concentration / Volume 99%+ purity; available in microgram to gram packages (research quantities)
Duration of Effects In animal models: rapid onset, prolonged (hours, dose-dependent)
Indications / Usage Areas Mu-opioid receptor studies, PET imaging, toxicology, forensic analysis, overdose modeling
Administration / Method Lab use: dissolution in solvents for in vitro/in vivo applications
Shelf Life 24-36 months+
Storage Conditions Cool, dry, airtight; below 25°C (refrigerated preferred), secure location
Package Contents Sealed vial, certificate of analysis, safety data sheet
Country of Origin Netherlands
Licensing / Certification Research-grade; Schedule I/II compliant standards
Safety Notes / Side Effects Extreme potency; not for human use; respiratory depression risk; requires advanced PPE and reversal agents
Quantity

5 grams, 10 grams, 25 grams, 50 grams, 100 grams, 250 grams, 500 grams, 1 KG

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